I have a vacuum block I'm making out of brass fittings. Currently I have my boost gauge (1/8" nylon line), GM MAP sensor (3/16"x12" [needs to be 1/4"]), and FPR (5/32") run off of a single line (5/32") from the manifold. I'm concerned that there's going to be a pressure drop or something from feeding so many things from one 5/32" line.

Is this going to cause any issues?

 

I would say that it won't. I assume you're doing this for a standalone (from the GM MAP sensor, it looks like you are). In my personal experience, the more dampening in the line for the MAP sensor the better.

What kind of setup are you running to where you have a shortage of vacuum ports anyways?

 

Haltech e6k with TII manifolds. I have, as I recall, 3 ports I can use for this, but it's easiest to just use one.