As I'm building my onw V mount and a friend is doing the welding (he's good) I'm free to chosse whatever design I want.

The OEM rad and all aftermarket ones have the end tanks up and under. For the V mount this is a rather unconvienent place. especially if you have the Oem style piping.

Basically I want my rad to have the endtanks on the side but keep the OEM dimensions (or close to it) and thicker.
hot side entering on the passenger side upper side of the end tank, cold side exiting on driver side lower end tank.

Has anyone done this before? What would be the pro's or con's?

 

There are a couple of good pics on that long vmount thread. you might want to check them out.

 

I know, but almost everybody uses modified Koyo's or another brand and these al have the conventional end tank design.

 

One disadvantage I can see would be that the water path length is longer (compared to the usual flow path) in what you want to do. This means less uniform temperature across the radiator, possibly resulting in less cooling efficiency.

 

I thought about having the end tanks on the side also but the issue I had with that design is that was that the mounting points would be covered up by the inlets/outlets to the radiator making packaging and installation more difficult.

The best design that I've seen is using the design seen in the Knightsports and Rotary Extreme.
1. This design makes the radiator a dual pass which offers increased cooling.
2. Packaging and installation is straightforward with plenty of clearance.
3. Inlets and Outlets are in locations that can be easily routed

 

You can certainly do it... depending on the rest of the infrastructure you're planning on using. Routing hoses from the side will present problems with A/C and powersteering paraphernalia, and with the stock fan shroud there may be a side to side clearance issue.