Here's a shot of Halwin running as a window on my OSX desktop:

http://img511.imageshack.us/img511/9...cture39mh3.png
http://img511.imageshack.us/img511/p...ng/1/w1024.png

And here's a shot of using OSX's built in spaces and VMWare Fusion, running OSX in the top left, Ubuntu linux in the top right, and Windows Vista in the bottom left:

https://img227.imageshack.us/img227/...cture40av2.png

dosbox runs the os apps well
 

Dapplegrey and DOSBox make running the e6k and e6x DOS apps from OS X pretty easy. apple.com/downloads has a driver for a bunch of the USB-Serial dongles too.